Annual report pursuant to Section 13 and 15(d)

STATEMENTS OF CASH FLOWS

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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Cash Flows from Operating Activities:      
Net loss $ (22,677) $ (22,461) $ (13,892)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation expense 3,117 3,867 3,252
Change in fair value of warrant liabilities 0 0 438
Issuance of common shares - Founders Agreement 0 14 1,269
Common shares issuable - Founders Agreement 2,296 3,919 3,024
Issuance of common shares for license expenses 0 0 633
Amortization of debt discount 0 324 89
Research and development-licenses acquired, expensed 400 3,160 2,525
Changes in operating assets and liabilities:      
Prepaid expenses and other assets (1,786) 100 (171)
Other receivables - related party 490 (756) (65)
Accounts payable and accrued expenses 2,699 1,883 1,790
Net cash used in operating activities (15,461) (9,950) (1,108)
Cash Flows from Investing Activities:      
Purchase of research and development licenses (400) (3,160) (2,525)
Net cash used in investing activities (400) (3,160) (2,525)
Cash Flows from Financing Activities:      
Proceeds from note payable, net of debt discount 0 0 2,554
Payment of note payable 0 (2,792) 0
Proceeds from issuance of common stock, net of offering costs of $0, $0 and $6,321, respectively 0 570 51,496
Cash received for issuance of founders shares 0 0 1
Net cash (used in) provided by financing activities 0 (2,222) 54,051
Net (decrease) increase in cash and cash equivalents (15,861) (15,332) 50,418
Cash and cash equivalents at beginning of period 35,086 50,418 0
Cash and cash equivalents at end of period 19,225 35,086 50,418
Supplemental disclosure of cash flow information:      
Cash paid for interest 0 20 56
Supplemental disclosure of noncash investing and financing activities:      
Debt discount associated with warrant liabilities 0 0 175
Issuance of common shares - Founders Agreement $ 3,919 $ 3,024 $ 0