Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Data (Unaudited) (Details)

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Quarterly Financial Data (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Total Revenue $ 3,031 $ 5 $ 127 $ 343 $ 332 $ 349 $ 351 $ 693 $ 3,506 $ 1,725
Operating expenses 14,923 9,392 6,805 9,126 6,271 6,299 6,823 5,107 40,246 24,500
Other income 273 43 39 18 21 22 24 31 225 0
Net loss $ (11,619) $ (9,344) $ (6,639) $ (8,765) $ (5,918) $ (5,928) $ (6,448) $ (4,383) $ (36,367) $ (22,677)
Basic and diluted net loss per common share $ (0.37) $ (0.32) $ (0.23) $ (0.35) $ (0.26) $ (0.26) $ (0.28) $ (0.20) $ (1.27) $ (1.00)