UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 14A INFORMATION

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CHECKPOINT THERAPEUTICS, INC.

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CHECKPOINT THERAPEUTICS, INC. *** Exercise Your Right to Vote *** Important Notice Regarding the Availability of Proxy Materials for the Stockholder Meeting to Be Held on June 13, 2018. CHECKPOINT THERAPEUTICS, INC. ATTN: GARRETT GRAY 2 GANSEVOORT STREET, 9TH FLOOR NEW YORK, NY 10014 Meeting Information Meeting Type: Annual Meeting For holders as of: April 16, 2018 Date: June 13, 2018 Time: 10:00 AM ET Location: Alston & Bird LLP 90 Park Avenue New York, New York 10016 You are receiving this communication because you hold shares in the company named above. This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. See the reverse side of this notice to obtain proxy materials and voting instructions.

Before You Vote How to Access the Proxy Materials NOTICE AND PROXY STATEMENT ANNUAL REPORT How to View Online: Have the information that is printed in the box marked by the arrow (located on the following page) and visit: www.proxyvote.com. How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request: 1) BY INTERNET: www.proxyvote.com 2) BY TELEPHONE: 1-800-579-1639 3) BY E-MAIL*: sendmaterial@proxyvote.com * If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow (located on the following page) in the subject line. Proxy Materials Available to VIEW or RECEIVE: XXXX XXXX XXXX XXXX XXXX XXXX XXXX XXXX Before You Vote How to Access the Proxy Materials How To Vote Please Choose One of the Following Voting Methods Vote In Person: Many stockholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the information that is printed in the box marked by the arrow (located on the following page) available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card. Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before May 31, 2018 to facilitate timely delivery.

Voting Items 2. The ratification of appointment of BDO USA, LLP as independent registered public accounting firm for the year ending December 31, 2018. 3. The approval of an amendment to our Amended and Restated Certificate of Incorporation to increase the number of authorized shares of common stock by 10,000,000 shares from 50,000,000 to 60,000,000 and decrease the number of shares designated "Class A Common Stock" from 15,000,000 to 7,000,000. 01) Michael S. Weiss 02) Scott Boilen 03) Neil Herskowitz 04) Lindsay A. Rosenwald, M.D. 05) Barry Salzman 1. Election of Directors Nominees: The Board of Directors recommends you vote FOR the following: The Board of Directors recommends you vote FOR proposals 2 and 3 NOTE: Such other business as may properly come before the meeting or any adjournment thereof.